diff --git a/src/time_domain_reduction/time_domain_reduction.jl b/src/time_domain_reduction/time_domain_reduction.jl
index a349f24525..ee3c3593c9 100644
--- a/src/time_domain_reduction/time_domain_reduction.jl
+++ b/src/time_domain_reduction/time_domain_reduction.jl
@@ -515,8 +515,18 @@ function get_demand_multipliers(ClusterOutputData,
             weighted_cluster_zone_sums[demandcol] += (W[m] / (TimestepsPerRepPeriod)) *
                                                      cluster_zone_sums[m][demandcol]
         end
-        demand_mults[demandcol] = zone_sums[demandcol] /
-                                  weighted_cluster_zone_sums[demandcol]
+        if iszero(weighted_cluster_zone_sums[demandcol])
+            if iszero(zone_sums[demandcol])
+                @debug "Zero demand detected; using neutral demand multiplier." demandcol
+                demand_mults[demandcol] = 1.0
+            else
+                @warn "Zero clustered demand with nonzero total; using zero multiplier." demandcol
+                demand_mults[demandcol] = 0.0
+            end
+        else
+            demand_mults[demandcol] = zone_sums[demandcol] /
+                                      weighted_cluster_zone_sums[demandcol]
+        end
         if v
             println(demandcol,
                 ": ",
diff --git a/test/test_time_domain_reduction.jl b/test/test_time_domain_reduction.jl
index 7a70df7425..eafebbc9f7 100644
--- a/test/test_time_domain_reduction.jl
+++ b/test/test_time_domain_reduction.jl
@@ -3,6 +3,7 @@ module TestTDR
 import GenX
 import Test
 import JLD2, Clustering
+import DataFrames
 
 include(joinpath(@__DIR__, "utilities.jl"))
 
@@ -62,4 +63,40 @@ for file in filter(endswith(".csv"), readdir(TDR_Results_true))
     Test.@test cmp_csv(joinpath(TDR_Results_test, file), joinpath(TDR_Results_true, file))
 end
 
+Test.@testset "Demand multiplier edge cases" begin
+    input_data = DataFrames.DataFrame(Demand_MW_z1 = zeros(2))
+    cluster_output = DataFrames.DataFrame(Symbol(1) => zeros(2))
+    weights = [2.0]
+    timesteps = 2
+    demand_mults = GenX.get_demand_multipliers(cluster_output,
+        input_data,
+        [1],
+        weights,
+        [:Demand_MW_z1],
+        timesteps,
+        [:Demand_MW_z1, :GrpWeight],
+        1,
+        1)
+    Test.@test demand_mults[:Demand_MW_z1] == 1.0
+
+    input_data = DataFrames.DataFrame(Demand_MW_z1 = [1.0, 2.0])
+    cluster_output = DataFrames.DataFrame(Symbol(1) => [0.5, 0.5])
+    weights = [2.0]
+    timesteps = 2
+    demand_mults = GenX.get_demand_multipliers(cluster_output,
+        input_data,
+        [1],
+        weights,
+        [:Demand_MW_z1],
+        timesteps,
+        [:Demand_MW_z1, :GrpWeight],
+        1,
+        1)
+    # Mirror the demand multiplier formula to validate expected scaling.
+    expected_multiplier = sum(input_data.Demand_MW_z1) /
+                          ((weights[1] / timesteps) *
+                           sum(cluster_output[!, Symbol(1)]))
+    Test.@test demand_mults[:Demand_MW_z1] == expected_multiplier
+end
+
 end # module TestTDR