diff --git a/README.md b/README.md
index 7b901e09..0ad5076b 100644
--- a/README.md
+++ b/README.md
@@ -23,6 +23,8 @@ Chrispens, K., Collins, M., Mai, D., Wankowicz, S. A., Fraser, J. S., & van den
 
 **Requirements**: Linux x86-64, CUDA 12, Python ≥ 3.11, < 3.14
 
+> **Note**: macOS (arm64) is supported for local development. The environments that pull CUDA builds are `linux-64` only; `pixi install -a` installs the rest, which is enough to develop and test most of the codebase.
+
 ### 1. Install Pixi
 
 ```bash
@@ -34,12 +36,15 @@ curl -fsSL https://pixi.sh/install.sh | sh
 ```bash
 git clone git@github.com:diff-use/sampleworks.git
 cd sampleworks
-pixi install -a   # install all environments
 ```
 
-> **Note**: `pixi install -a` resolves all environments. This (currently) requires CUDA 12 and will fail on machines without it.
+Sampleworks is split across several Pixi environments: one per generative model, plus environments for analysis and development. For a complete list, run `pixi workspace environment list`. To install all that are compatible with your machine, run:
+
+```bash
+pixi install -a
+```
 
-Each generative model has its own Pixi environment. Install only what you need:
+Alternatively, install only what you need:
 
 ```bash
 pixi install -e boltz      # Boltz-1 / Boltz-2