+
+ The inhibition constant {variables.ki} is analogous to{" "}
+ Kd, but for our competitive inhibitor . It
+ can be determined by finding the {variables.ic50} — the
+ concentration of at equilibrium where the amount of{" "}
+ formed is reduced by half. You can think of it as{" "}
+
+ "how little do I need to cut formation in
+ half?"
+ {" "}
+
+
+ -
+ high {variables.ki} ={" "}
+ low inhibitor potency
+
+ -
+ low {variables.ki} ={" "}
+ high inhibitor potency
+
+
+
+ A reaction with a high {variables.ki}{" "}
+ means you need a lot of to cut formation in
+ half, so the inhibitor has low potency. A{" "}
+ low {variables.ki} means you don't need
+ very much , so the inhibitor has{" "}
+ high potency.
+
+
+