Initial release of an Enterovirus A71 dataset - #467
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Enterovirus A71 dataset
This pull request introduces the initial release of a Nextclade dataset for Enterovirus A71 (EV-A71), designed for lineage classification, subgenotype assignment, mutation analysis, sequence quality control, and phylogenetic placement. The dataset uses a reconstructed ancestral sequence as the reference, which is genetically closer to currently circulating EV-A71 strains and supports more accurate analyses compared to historical prototypes.
The most important changes are:
Dataset Documentation and Metadata:
README.mddescribing the dataset's scope, features, clade definitions, reference types, and usage guidance, including authorship and contact information.CHANGELOG.mdnoting this as the initial release and providing a link to Nextclade dataset documentation.Reference Data and Annotation:
reference.fastacontaining the inferred ancestral EV-A71 sequence, which serves as the main reference for mutation calling and sequence alignment.genome_annotation.gff3with detailed genome feature annotations (e.g., CDS for VP4, VP2, VP3, VP1, and non-structural proteins) based on the BrCr prototype sequence.Checklist