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Guidance on --t2e-l1-pi6 for low-heritability T2E trait — Level 1 model fails to converge without it

Status: Open.

#691 In rgcgithub/regenie;

· RamonaZwamborn opened on Aug 14, 2026

"ERROR: need at least one phenotype" even I have a pheno column

Status: Open.

#690 In rgcgithub/regenie;

· ChenJiang11 opened on Aug 12, 2026

Inflation of beta-values from logistic analysis - it is version specific

Status: Open.

#684 In rgcgithub/regenie;

· nievergeltlab opened on Mar 2, 2026

Ordinal/categorial traits

enhancementNew feature or requestNew feature or request

Status: Open.

#681 In rgcgithub/regenie;

· JordanBoulais opened on Feb 13, 2026

Support vcf/bcf format for structural variants

enhancementNew feature or requestNew feature or request

Status: Open.

#677 In rgcgithub/regenie;

· jjfarrell opened on Jan 9, 2026

Conditional analysis with multiple variants

Status: Open.

#676 In rgcgithub/regenie;

· Nobuyuki-Enzan opened on Dec 31, 2025

Guidance for Gene-level test Gene_P

Status: Open.

#675 In rgcgithub/regenie;

· zyh4482 opened on Dec 22, 2025

how to define minMAC for generic burden test?

Status: Open.

#674 In rgcgithub/regenie;

· sinhanushka12 opened on Dec 15, 2025

Feature request: Allow writing masks to plink2 (pgen) file format so that non-integer weighted genotypes can be captured

Status: Open.

#671 In rgcgithub/regenie;

· dvg-p4 opened on Nov 6, 2025

P-values not calculated in interaction testing

Status: Open.

#669 In rgcgithub/regenie;

· IchigoJiken opened on Oct 21, 2025

Regenie requires FID to be present in .psam files although it is optional in the spec

Status: Open.

#666 In rgcgithub/regenie;

· pettyalex opened on Sep 28, 2025

Feature request: Support providing both domain and weights at the same time

enhancementNew feature or requestNew feature or request

Status: Open.

#655 In rgcgithub/regenie;

· dvg-p4 opened on Aug 18, 2025